What is ACTH ACTH Test How-To Reference Range Normal Value
ACTH is a hormone secreted in the pituitary gland in the brain. The ACTH test measures the adrenocorticotropic hormone, ie ACTH, in the blood. The main function of the hormone ACTH is to control the level of cortisone in the body. Cortisol hormone is secreted by the adrenal glands and regulates blood pressure and blood sugar in the body. The ACTH test is performed to find the cause of some hormonal disorders in the body. In the early morning, the normal ACTH hormone level in the blood ranges from 9 to 52 pg / mL (2 to 11 pmol / L). Normal values may vary slightly depending on the laboratory.
What is the ACTH Test?
If the patient suspects of hormone problems, the doctor takes the ACTH test. This test is used to diagnose situations that include:
Cushing’s disease in which the pituitary gland produces too much ACTH hormone
Cushing’s syndrome, a disease in which the adrenal glands produce too much cortisol
Addison’s disease in which the adrenal glands do not produce enough cortisol
Hypopituitarism, disease that prevents the pituitary gland from producing enough vital hormones
What Are the Normal Values of ACTH?
In adult women: 5-27 pg / mL or 1.11 – 6 pmol / L
In adult males: 7-50 pg / mL or 1.55 – 11.1 pmol / L
Prior to puberty: 7-28 pg / mL or 1.55 – 6.2 pmol / L
After puberty: 2-49 pg / mL or 0.44 – 10.78 pmol / L
Why is ACTH Height?
The reasons for the height of ACTH are:
Adrenal glands do not produce enough cortisol disease (Addison’s disease)
Adrenal glands do not produce enough hormones (congenital adrenal hyperplasia)
One or more of the endocrine glands overactive or tumor-induced (multiple endocrine neoplasia type I)
Producing too much ACTH caused by the presence of a noncancerous tumor in the pituitary gland (Cushing’s disease)
Rare type of tumor (ACT), which rarely produces ACTH (ectopic Cushing’s syndrome) (such as lung, thyroid or pancreas)
What Are the Symptoms of Height in ACTH?
Nausea and vomiting
Stomach and back pain
How to Reduce ACTH Height
You should go to the Endocrinology department to treat ACTH elevation. The doctor will first determine the cause of this condition and apply the necessary treatment. For the treatment of low ACTH, the doctor may recommend using the following vitamin pills:
Why Is ACTH Low?
The reasons for the decrease in ACTH are:
The most common cause of decreases in ACTH level is elevation in cortisol level in the body. ACTH hormone stimulates the production of cortisol secreted by the adrenal glands. Cortisol is an important hormone for suppressing the immune system, keeping blood pressure at a certain level, regulating protein, glucose and fat metabolism. Normally, when the ACTH level is high, the low cortisol level increases as the ACTH level decreases. Other causes of low ACTH hormone levels are:
Side effects of some drugs, such as cortisone
Inadequate production of hormones such as pituitary gland ACTH (hypopituitarism) in the body
It is a tumor in the adrenal glands, which leads to too much cortisol release in the body.
Use of glucocorticoid drugs (these drugs suppress ACTH production)
Hypopituitarism (pituitary failure)
Pituitary gland tumor
Pituitary surgery or radiotherapy
Damage or trauma to the pituitary gland
Having a tumor in the hypothalamus
To receive hypothalamus surgery or radiotherapy for tumors
Injury or trauma in the hypothalamus
What Are the Symptoms of ACTH Loss?
Nausea or vomiting
Low blood sugar
How Can ACTH Impairment Be Treated?
You should go to the Endocrinology department for treatment of low ACTH. The doctor will first determine the cause of this condition and apply the necessary treatment. For the treatment of low ACTH, the doctor may recommend using the following vitamin pills:
Doing 1 hour of sports can help increase ACTH level.
How is the ACTH Test done?
For the ACTH test, a blood sample is taken from the patient’s arm with an intravenous needle and a blood test is performed.
Blood can be taken both morning, afternoon and evening. This leads to differences in the level of the ACTH hormone in the blood.
What to Do Before the ACTH Test?
On the day of the ACTH test, the patient should not eat or drink anything before midnight. That night the patient should get a good night’s sleep. The patient should follow the steps of the doctor. In addition, the doctor will be doing all the drugs, plants, vitamins and supplements ACTH test should know. These include drugs that are sold without a prescription and illegal drugs.
What Can ACTH Affect Test Results?
ACTH test results can be affected by, for example, such events can increase or decrease ACTH levels.
Being under high stress
Recently experienced trauma
Using drugs including Streoid, hormone or insulin
Sleep the night before the test