Lipase is a type of enzyme produced by the pancreas, which is transferred to the small intestine, used for the transport and digestion of lipids such as triglycerides, fats and oils. What is the normal, low and high lipase level in our article ? We have included the subject.
Pancreas is one of the important organs of the digestive system that helps the digestive process in various ways. “Human pancreatic lipase (HPL)” helps in the breakdown of fats. Thus it converts triglycerides to monoglycerides and free fatty acids. HPL is one of the main lipases of the human digestive system. Hepatic lipase (HL) endothelial lipase and lipoprotein lipase are other important lipases in the human body.
Lipase normal values
The normal lipase values that may be a reference may vary from laboratory to laboratory and from country to country. Generally, lipase levels of “7 to 58 units / L” are considered normal. But depending on the characteristics of the country, some laboratories accept the ratio of adan 0 160 units / L leri in the normal range for lipase. Ediy The normal values of lipase may vary slightly from person to person. The test result may help to detect acute pancreatitis (pancreatic inflammation), chronic pancreatitis, and other pancreatic disorders, as well as to diagnose and treat cystic fibrosis, celiac disease, and Crohn’s disease.
Amylase is another important enzyme that is secreted in the pancreas with lipase. Mostly, lipase levels are checked and amylase levels are also checked. Amylase is secreted by other glands such as salivary glands. In the case of acute pancreatitis, the levels of amylase and lipase increase significantly.
Measuring pancreatic lipase is the best way to detect pancreatic problems. Fractures such as fever, loss of appetite, nausea, severe abdominal or back pain occur in the failure to perform the function of the pancreas, then the lipase test is requested. This test can be performed periodically to monitor the efficacy of pancreatitis treatment.
The level of lipase within the normal range helps to maintain digestive health. In the case of pancreatic inflammation, lipase levels generally increase more than 5 to 10 times the upper limit of the normal value. This rate rises within one or two days after an acute pancreatitis attack and remains elevated for about one week.
The use of certain drugs , such as codeine, indomethacin and morphine, may also increase lipase levels. The elevation of the lipase level is sometimes asymptomatic and may not give any indication. In some people, abdominal pain, sweating, nausea, vomiting, fatigue, etc. can lead to symptoms.
Clogging of the pancreatic duct, pancreatic cancer and other pancreatic diseases may also increase lipase level. Lipase levels above normal may also indicate viral gastroenteritis, gastric ulcer, or obstruction. Increased lipase levels due to pancreatitis may be reversed to the normal level following drug use and pancreatitis diet plan.
Reduction of lipase levels often indicates permanent damage to lipase-producing cells in the human pancreas. Cystic fibrosis (a congenital disease that shows that the person’s lungs, intestines and pancreas are obstructed with thick mucus), as well as people with chronic diseases that may affect the pancreas, such as celiac disease or Crohn’s disease, may often be associated with a low level of lipase.
Low lipase can also cause indigestion. People with persistent indigestion problems should check their lipase levels. In the case of lipase deficiency, treatment with lipase supplements may be performed.
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