White blood cells (WBCs), also known as leukocytes and white blood cells, are a very important part of your immune system and help you fight infections by destroying viruses, bacteria and microbes in the body. These cells are produced in the bone marrow and circulate throughout the body. Your doctor will ask you for a WBC count test, which is part of your total blood count, to check the number of white blood cells in your body. The exact amount for leukocyte height varies from laboratory to laboratory. For adults in general, more than 11,000 white blood cells (leukocytes) in a microliter of blood are considered leukocyte height.
There are different types of white blood cells, but they are basically divided into two main categories: Granulocyte and Agranulocytes. Granulocytes are a combination of three types of white cells, including basophils, neutrophils, and eosinophils, all of which are responsible for the elimination of harmful microorganisms.
Blood tests measure the number of all these cells. Normally, a healthy body contains between 3,700 and 10,000 white blood cells. Changes in these numbers may occur due to stress, exercise and disease.
WBC Height Causes
The increase in the number of white blood cells (leukocytes) is usually caused by viral or bacterial infection, but parasitic and fungal infections can also increase the number of leukocytes. In the case of a bacterial infection, your immune system stimulates the bone marrow to increase the number of white blood cells to fight infection. As with viral infections, elevation of leukocytes occurs when the immune system attempts to remedy the infection.
Inflammation and allergy
Inflammation and allergy are also factors that increase the number of white blood cells. Inflammations such as rheumatoid arthritis increase the amount of leukocytes. Injury with tissue damage in the surgical procedure for heart attack and burn can also cause leukocyte height. Allergic reactions and the body’s fight against the allergen causing asthma can also trigger white blood cell production.
If you are under severe emotional stress, you may experience an increase in your leukocyte count. Serious physical stress, especially through exercise, may increase the levels of cortisol and other hormones and increase the levels of white blood cells in your bloodstream.
Bone marrow diseases
Bone marrow diseases can also cause an increase in white blood cells. Leukemia is a common complication and is a type of cancer that produces a lot of white blood cells in the bone marrow. Polycythemia Vera, which causes a mutation in a gene called JAK2, is another bone marrow disorder that increases the number of white blood cells in your body. Myelofibrosis is also associated with bone marrow-related diseases that trigger the rise in leukocyte count.
Immune system diseases
Why does the leukocyte count rise? An answer to this question may be an autoimmune disease such as Graves or Crohn’s disease. If you suffer from one of these diseases, it is important for your doctor to check your leukocyte count.
Side effects of drugs
Medications used to treat mental health, inflammation, and even cancer can also increase leukocyte levels. A 2001 study showed that lithium drugs can send chemical messages to the immune system and generate more white blood cells.
Excessive smoking habits can lead to chronic obstructive pulmonary disease (COPD) or lung respiratory diseases such as chronic bronchitis or emphysema. These diseases cause oxygen intake during breathing and increase inflammation in your lungs and airways. Your body produces more white blood cells to combat these diseases.
Other causes of leukocyte height
Acute lymphocytic leukemia
Acute myelogenous leukemia (AML)
Allergies, especially severe allergic reactions
Chronic lymphocytic leukemia
Chronic myelogenous leukemia
Drugs such as corticosteroids and epinephrine
Bacterial or viral infections
Hypothyroidism, ovulation and estrogen abnormalities
Polycystic Ovary Syndrome (PCOS)
Thyrotoxicosis and Addison’s disease
How to reduce the leucocyte height, which doctor to go?
If you are suffering from leucocyte elevation, you should consult a Internal Medicine doctor. Peripheral smear, t (9; 22) and jak-2 gene tests, crp test and bone marrow test, your doctor will determine the cause of this condition and apply the necessary treatment.
If the leukocyte is caused by infection, the doctor will prescribe you antibiotics.
If the leukocyte is elevated due to cancer, chemotherapy and radiotherapy are applied for treatment.
Anti-inflammatory anti-inflammatory drugs are also alternative treatment methods for inflammation-induced leukocyte elevation.
If the leukocyte is too high, blood exchange is performed.
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