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What is Toxic Goitre?

What is Toxic Goitre?

The thyroid gland is a diaper just below the Adam diamond. The thyroid glands secrete hormones that help regulate bodily functions, such as the process of regulating metabolism, the process of transforming food. It is also an effective diaper on heart rate, respiration, digestion and psychology. The growth of the thyroid gland is called goiter. Thyotoxicosis and also known as hyperthyroidism, toxic goitre occurs when thyroid hormone produces excessive hormones when overworked . Toxic goitre is also called inner goiter among the population. In other words, thyroid hormones are found in the blood too much because of the problems caused by them in the body. Toxic goiter is the progression of normal goiter disease. It is usually seen in older adults. Risk factors include being a woman and being over 55 years of age. This disorder is rarely encountered in children.

Causes of toxic goiter (Thyrotoxicosis and Hyperthyroidism)

Intense stress

Feeling of extreme sadness (especially after death, such as death, dismissal and earthquake)

Basedow-Graves disease

Toxic adenoma (single nodule secreting more hormones)

Toxic multinodular goiter

Thyroiditis (Thyroiditis)

Excessive thyroid hormone

Symptoms of toxic goiter

Fatigue, weakness, weakness

Flicker in hands

Sudden Weight Loss

Flutter in the heart

Frequent large toilet

Sensitivity to heat

Increase in appetite

Swollen eyes, swelling of the eyelids

Excessive sweating

Eyes grow outward

Irregular period

Muscle cramps

Irritation, severe anger


Weight loss

Hair loss

Sweating in the palms

Nausea Vomiting

How is toxic goiter diagnosed, what tests are performed?

In physical goitre on toxic goitre, one or more nodules are encountered in the thyroid. Acceleration may also occur in the heartbeat.

Other tests for the diagnosis of toxic goiter are as follows;

  • Serum thyroid hormone levels (T3, T4)
  • Serum TSH (thyroid stimulating hormone)
  • Thyroid intake and screening or radioactive iodine intake
  • Thyroid ultrasonography

Treatment of toxic goiter

Toxic goitre can be treated with radioactive iodine without surgery after extensive examinations. According to the American school, radioactive iodine is the only option. However, it is mandatory for patients to use thyroid hormone after surgery or after radioactive iodine.

Basedow-Graves disease, toxic adenoma and toxic multinodular goitre are treated by surgical intervention if there is no serious obstacle for surgery. If surgery is not possible, radio-active iodine may be treated.

From head to toe in toxic goitre all functions work very fast. The heart works excessively, the body’s heat generating center works too extreme. Coma may occur most of the time. Because all systems work unnecessarily. Treatment of toxic goiter is also possible with drugs that can reduce the secretion of thyroid hormones.

The use of antithyroid drugs for toxic goitre is also a possible treatment method. There are two antithyroid drugs in our country. These are ‘propylthiouracil’ and ‘methimazole’. It can be used to treat the exacerbation of the disease as well as to prepare for surgical treatment or radioactive iodine treatment. Before using these drugs, it should be taken into consideration that patients may need to use these drugs for months to years and when the treatment is interrupted, the disease may flare up again in either patient.

If surgery for the treatment of toxic goiter is preferred, the thyroid hormones of the patient should be temporarily rotated normally; otherwise, when the patient receives general anesthesia, his heart may not be restrained and his heart rhythm deteriorates and he may fail. Due to these very serious cardiac complications, the death of the patients may even occur.

In the operation performed for the treatment of toxic goiter, the vocal cords may be paralyzed as a result of damage to the nerves (laryngeal recurrent nerves) in the operation performed for the treatment of toxic goiter and the patient may lose its voice after surgery. In one person there are 2 sound wires; if the nerve to the person is damaged, a single vocal cord of the patient may be paralyzed, muted and quality may be impaired, but if the nerve to both voices is damaged during surgery, both vocal cords in the patient will be paralyzed and the patient cannot talk. Furthermore, in one or two vocal cord palsy, the patient’s breathing during sleep is impaired, and the sleep pattern may also deteriorate as the patient goes to sleep at night while the oxygen to the brain decreases. These symptoms are partially diminished over time, but not completely.

What happens if toxic goiter is not treated?

Toxic goiter is an extremely serious disease. If treatment is delayed, especially in patients with cardiovascular disorders. Rhythm disorder in the heart, heart growth, heart failure, high blood pressure. Sudden death can be seen in patients with thyroid attack.

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