Which Treatment Should Be Applied to Which Infertility Case?

Infertility can be a big burden on your emotional health, but if you are infertile and hope to have a baby, there are many options to hope for. Science continues to evolve, treatment options are getting better, and more babies are born each year using one of the techniques listed below. In fact, more than half of couples experiencing infertility can become pregnant after treatment, and high-tech and expensive treatments such as IVF are not included.

Which Treatment Should be Applied to Which Infertility Case?

Which technique you need depends heavily on your cause of infertility. How much it will cost depends on some factors such as where you live.

Fertility Pills

How it works: These drugs, taken in injection or pill form, release hormones that initiate ovulation to increase egg production and make the uterus more suitable for embryo placement.

Who is it good for: Women who do not ovulate regularly and in cases with poor sperm quality. Avoid scarring caused by endometriosis with damaged or blocked fallopian tubes.

Success rates: 40-45% of women who take the pills and ovulate become pregnant, while those who have a needle have up to 50% success rate.

Pros: These drugs are generally the first option for infertility treatment because they are low in costs and easy to use.

Cons: Bloating, headaches, hot flushes and nausea. Side effects are worse in the needles, and multiple births, premature birth, and the formation of large ovarian cysts can occur.

Artificial Insemination

How it works: A specially prepared sperm is placed directly in the uterus through a thin, flexible instrument and is the most common fertility method. If you choose this method, your doctor may ask you to increase your chances of fertilization by taking fertility pills.

Who is good for: It is good if the sperm of the man has slow movements or low quality, and also if the number of sperm is low. It is also used in women who produce antibodies against their partner’s sperm, or in women whose sperm have trouble reaching the egg, because the vagina fluid is too dense, acidic, or inadequate.

Success rates: Depending on the age of the woman and the quality of the sperm of the man, but in general, there is a 15-20% success rate in each trial, after 6 attempts, around 60-70% success rate is achieved.

Pros: A simple procedure that can be done in the doctor’s office.

Cons: May cause multiple births due to possible side effects of fertility pills.

IVF Treatment

How it works: It is a multi-step process and during this process your eggs are collected and fertilized in the laboratory with sperm. When embryos develop, one or two are implanted into the uterus, the rest are stored.

Good for: Women with endometriosis scars, women with blocked or severely damaged fallopian tubes, and those of advanced age. Also in cases with inexplicable infertility couples and men with very low sperm quality.

Success rates: Varies by age. 41% of women under 35, 32% of those aged 35-37 and 23% of those aged 38-40 become pregnant.

Pros: Couples with serious fertility problems can become parents.

Cons: Treatment is costly and physically tiring. Also before every try fertility medicine may require use.


How it works: The surrogate mother carries the baby for another woman. With artificial fertilization, the surrogate mother becomes pregnant, while the couple’s embryo is used, such as the father’s sperm or IVF treatment.

Who is it good for: Mothers who cannot bear babies due to illness, hysterectomy or infertility. In rare cases, it can be used if both partners are infertile.

Success rates: Depends on egg and sperm quality. On average, the live birth rate is around 5-30% per trial.

Pros: Couples with fertility problems can get pregnant.

Cons: Costs are high. Couples may feel as if there is no pregnancy. They also have to deal with many legal obligations.

Reproductive System Surgery

How it works: With surgery, anatomical disorders, scars and blockages are treated in both men and women.

Who is it good for: couples who are diagnosed with a disease or abnormality.

Success rates: Depends on discomfort and severity, as well as age. One study found that women who received laparoscopic treatment for endometriosis had twice as much pregnancy rates as those who did not receive this treatment.

Pros: If we ignore the pain and ailments associated with the disease, it may increase the likelihood of pregnancy.

Cons: Some surgeries are more extensive than others, which prolongs the risk, cost, and resting process.

Gamet Intrafallopian Transfer

How it works: Eggs are collected from the woman, they are mixed in the petri dish with the sperm of the man, and then transferred directly to the fallopian tubes where fertilization will occur.

Who is it good for: In cases where the woman has at least one fallopian tube working, or when the man has poor mobility with few sperm. In addition, those who refuse IVF treatment for religious and moral reasons and those with inexplicable infertility.

Success rates: In one attempt, pregnancy is 25-30%, young, healthy women are more likely to succeed.

Pros: It provides fertilization in a natural environment.

Cons: There is no immediate confirmation that fertilization has occurred. It is more complicated than IVF treatment because laparoscopy is required to place the egg and sperm into the tubes. Generally, if more than one egg is used, the risk of multiple births is higher than normal.

Zygote Intrafallopian Transfer

How it works: It is like IVF treatment, but in this case the embryo is transferred to the fallopian tubes, not the uterus.

Who is it good for: Inexplicable infertility couples or in men with low sperm count. The woman must have at least one tube open or have ovulation problems.

Success rate: Like most assisted reproductive techniques, it depends on age and health. In general, 36% of those who experiment are pregnant while 29% give birth.

Pros: Fertilization of the egg-sperm mixture is known before being placed in the fallopian tubes. Therefore, fewer eggs can be used, which reduces the risk of multiple births.

Cons: It is an intrusive operation since laparoscope is used, which increases the risk and costs compared to other treatments. This method and the gamet intrafallopian transfer method are rarely used.

Source: Prof. Dr. Bulent Shaving

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